Discover how our work in translational research drives meaningful change both in a clinical setting and in everyday life. Through utilizing the Translational Science Benefits Model (TSBM) framework, we not only measure research effectiveness but also ensure our efforts translate into tangible, real-world benefits. Explore inspiring success stories that showcase the positive impact our initiatives have had on patients, communities, and the broader scientific landscape.
Translational Science Benefits Model (TSBM) Case Studies
The TSBM is a framework that helps researchers measure and demonstrate the real-world benefits of their work across four domains: clinical, community, economic, and policy. It identifies 30 specific benefits and goes beyond publication counts to track broader impacts on health and society.
Studying Renin to Improve Sepsis Outcomes
This initiative, led by Dr. Ashish Khanna, focuses on the renin-angiotensin-aldosterone system (RAAS) in the quest to identify biomarkers for earlier diagnosis and personalized treatment of septic shock.
The project unites multiple healthcare sites, emphasizing collaboration to drive advances in patient care. By seeking to guide future clinical guidelines, reduce disparities, and enhance outcomes for high-risk patients, this initiative exemplifies the transformative potential of translational science. The anticipated benefits extend far beyond the laboratory, promising to revolutionize the management of septic shock and improve survival rates worldwide.
Learn More The project unites multiple healthcare sites, emphasizing collaboration to drive advances in patient care. By seeking to guide future clinical guidelines, reduce disparities, and enhance outcomes for high-risk patients, this initiative exemplifies the transformative potential of translational science. The anticipated benefits extend far beyond the laboratory, promising to revolutionize the management of septic shock and improve survival rates worldwide.
Translating Innovating Imaging Technology to Clinical Use for Premature Infants
Led by Jared A. Weis, PhD, this project targets necrotizing enterocolitis (NEC), a serious intestinal disease in premature babies.
Drs. Victoria Weis (Wake Forest Institute for Regenerative Medicine), Jared Weis (Biomedical Engineering), Cherrie Welch (Neonatology), and Kristen Zeller (Pediatric Surgery) collaborated to developed a non-invasive imaging technique called photoacoustic imaging (PAI) to help diagnose necrotizing enterocolitis (NEC) in premature infants. Their pilot study showed PAI can safely measure key signs of NEC, like oxygen levels and intestinal movement, in newborn rats. This child-focused research could lead to better, faster diagnosis and care for vulnerable babies.
Learn More Drs. Victoria Weis (Wake Forest Institute for Regenerative Medicine), Jared Weis (Biomedical Engineering), Cherrie Welch (Neonatology), and Kristen Zeller (Pediatric Surgery) collaborated to developed a non-invasive imaging technique called photoacoustic imaging (PAI) to help diagnose necrotizing enterocolitis (NEC) in premature infants. Their pilot study showed PAI can safely measure key signs of NEC, like oxygen levels and intestinal movement, in newborn rats. This child-focused research could lead to better, faster diagnosis and care for vulnerable babies.
Success Stories
CTSI success stories highlight the transformative impact of its programs. Researchers have leveraged CTSI resources to secure major grants, develop new diagnostics and therapies, and foster community engagement, ultimately improving patient outcomes and public health.
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Translating Innovative Imaging Technology to Clinical Use for Premature Infants: A Wake Forest CTSI Pilot Program Success Story
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Advancing Sepsis Research: A Wake Forest CTSI Pilot Program Success Story
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The Impact of Wake Forest CTSI’s Pilot Program on Advancing Emergency Cardiac Care Research
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Deepak Palakshappa Collaborates with Wake Forest CTSI to Address Patient Food Insecurity
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Dr. Jaime Hughes and Team’s WalkOn! Program Takes Strides Forward Receiving an Outstanding Award: A Wake Forest CTSI Pilot Success Story
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Wake Forest CTSI Pilot Program: Supporting Research and Collaboration
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Cite the CTSA
A key measure of a program’s productivity is its number of attributed publications. All publications, press releases, or other documents that result from the utilization of any Wake Forest CTSI resources, including the presentation of data and images acquired through CTSI programs, are required to credit the CTSI and comply with NIH Public Access Policy (submission to PubMed Central).
Examples:
- "The authors gratefully acknowledge use of the services and facilities of the...**, funded by the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through Grant Award Number UM1TR004929."
**Please indicate the type of resource utilized. For example, Clinical Research Unit, Translational Imaging Shared Resource (TISR), etc. - "We would like to acknowledge the... *** of the Wake Forest Clinical and Translational Science Institute (WF CTSI), which is supported by the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through Grant Award Number UM1TR004929."
***Please indicate the type of assistance received. For example, CRU assistance, statistical assistance, editorial assistance, etc.
- "The project described was supported by the National Center for Advancing Translational Sciences (NCATS), National Institutes of Health, through Grant Award Number UM1TR004929. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH."
- "The project described was supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grant K12TR004931. The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH."