The Clinical and Translational Science (CTS) Pilot Program invests in investigators with innovative ideas and established scientists expanding their domain expertise. We support pilot projects that will pilot innovative approaches for addressing important roadblocks in translational science with a focus on the Academic Learning Health System (aLHS). While addressing these translational roadblocks, these projects will also apply a health equity lens and facilitate multidisciplinary, team-based, and patient-centric science that is broadly generalizable. 

The CTS Pilot Program supports two RFAs each year: The Science of Translation RFA and the Translational Research RFA. Both RFAs aim to fund one-year pilot projects at $40,000 each. 

Science of Translation

The purpose of the Science of Translation RFA is to support new and innovative research projects relevant to the science of translation. These pilot projects must be focused on advancing translational science and not just be translational in nature. They must be focused on understanding a scientific or operational principle underlying a step of the translational process with the goal of laying the scientific foundation for improvements in translational efficiency that will accelerate the realization of interventions that improve human health. 

2024-2025 Science of Translation Pilot Recipients

Halley Alexander Photo
Halley Alexander, MD
Assistant Professor, Neurology

“Applying the Multiphase Optimization Strategy Framework (MOST) to Physical Activity Interventions for Neurological Populations”

Jaime Hughes
Jaime Hughes, PhD, MPH, MSW
Assistant Professor, Implementation Science

“Engaging Rural Older Adults and Communities in the Refinement and Implementation of WalkOn!”

Ashish Khanna Photo
Ashish Khanna, MD
Professor, Anesthesiology

“Precision-Based Renin Assessment in Septic Shock Outcomes”

Amy McMichael Photo
Amy McMichael, MD
Professor, Dermatology

“Identifying Genetic Risk Factors for Traction Alopecia in African Americans”

Translational Research Pilots

The purpose of the Translational Research RFA is to support high impact pilot projects that focus on catalyzing the translation of discoveries to treatments or the delivery of care. The ultimate aim of this RFA is to make research investments that maximize healthcare value and improve population health. These projects should fall into one of the Translational Science Spectrum categories (Basic Research, Preclinical Research, Clinical Research, Clinical Implementation, Public Health). 

2024-2025 Translational Research Pilot Recipients

Reto Asmis Photo
Reto Asmis, PhD
Professor, Molecular Medicine

“Role of Hematopoietic Monoamine Oxidase A in Experimental Autoimmune Encephalomyelitis (EAE)”

Rohan Mahabaleshwarkar Photo
Rohan Mahabaleshwarker, MD
Assistant Professor, Implementation Science

“Validation of a Pharmacy Risk Score in Patients with Diabetes and Hypertension”

John Salsman Photo
John Salsman, PhD
Professor, Social Sciences and Health Policy

“Supporting Spirituality in Young Adults with Cancer Using a Digital Health Approach: A Feasibility Study”

Jared Weis Photo
Jared Weis, PhD
Assistant Professor, Biomedical Engineering

“Clinical Translation of Photoacoustic Imaging for Assessing Infant Intestinal Health and Necrotizing Enterocolitis”

Jeffrey Willey Photo
Jeffrey Willey, PhD
Professor, Radiation Oncology

“Osteoclast and Neuronal Crosstalk as a Mechanism for Chest Wall Pain in Lung Cancer Patients Receiving Thoracic Radiosurgery”