Clinical Research Unit

• Adult and Pediatric Waiting Rooms
• 15 Exam Rooms
• 2 Procedure Rooms
• 6 Infusion Rooms
• 4 Observation Rooms
• 3 Consult Rooms
• Study Staff Workroom
• Participant Lounge
• Metabolic Kitchen
• CLIA-Certified Processing Laboratory 

CRU Bionutrition services support WFBH researchers with the design, planning, and implementation of any nutrition components within their research protocols.  Our staff and facilities include Registered Dietitians (RDs) with extensive research experience and a fully-staffed Metabolic Kitchen.  The following services are provided.

Food Service

• Research diet development, analysis, and preparation
• Computer-assisted menu planning for controlled-nutrient, weighed, and metabolic diets
• On-site and pack-out research diet feeding
• Recipe development
• Computer-assisted food weigh-back system
• Aliquot preparation for meal assays
• Doubly-labeled water testing
• Food sampling to support nutrition counseling themes
• Healthy snacks for fasting visits

Metabolic Assessment

• Anthropometric body measurements
• Bioelectrical impedance (BIA) measurement
• Indirect calorimetry (RMR) testing
• Dietary intake data collection and analysis from dietary recalls or food records using Nutrition Data System for Research (NDSR) software
• Nutrition screening and evaluation for feeding study eligibility
• Nutritional status and dietary history assessments
• Dietary compliance monitoring and assessment
• Vitamin, mineral, and herbal supplement intake assessment
• Food frequency questionnaire administration and analysis

Nutrition Education

• Nutrition education and counseling by Registered Dietitians
• Development of protocol-specific educational materials
• Development, implementation, and analysis of self-monitoring tools

Additional Support Services

• Consultation for development of nutrition components for grant applications and publications
• Collaboration with research team to develop nutrition-related research forms
• Student/intern training

The CRU laboratory staff provide consultation on specimen collection and testing procedures as well as processing of blood, saliva, sputum, urine, and fecal specimens. The laboratory is equipped with -70 and -20 freezers, refrigerators, refrigerated centrifuges, micro-centrifuges, micropipettes, and a biological safety cabinet (A2) hood. All freezers, refrigerators and ambient temperatures are monitored 24 hours a day via SPOT system. All Laboratory Technicians have completed CITI and GCP training.
Available services include:

• Isolation of Specific Cells (examples: PBMCs, T-Cells, RNA) 
• Collaboration with LabCorp and Institutional Core Laboratories
• IV Glucose Tolerance Testing and Oral Glucose Tolerance Testing
• Non-Waived Testing (YSI 2300 STAT Plus Glucose Analyzer)
• Waive Testing (HemoPoint and Urine Pregnancy) 
• Real Time Results Reporting for glucose, hemoglobin and hematocrit.
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Specimen Processing
• Preparation and Routing of Specimens for Immediate Analysis
• Preservation and shipment of Specimens for Transport, Ambient, Refrigerated, and Frozen on Dry Ice
• Processing of Blood, CSF, Sputum, Saliva, Urine, and Feces.
• Storage and shipment of pre-cut Tissue samples.
• Short-Term Repository Storage
• Validation of Point of Care Testing Instruments, Including Development of QC and QA Programs

Dry Ice CRU In-House Purchase:

Thank you for your interest in purchasing dry ice.  The cost per kg is $3.22 for industry studies and $2.22 for all other studies.  You can pick up the dry ice in the Clinical Research Unit, Main Floor Progressive Care Building. We require a 24 hour notice prior to pick-up.  We do understand that circumstances may arise that you need dry ice ASAP so please call 336-716-9752 to make sure we have enough in stock. 

To setup an account please complete the form below and send to cru@wakehealth.edu. A SPID number will be assigned and emailed to you within 24 hours.

Dry Ice SPID Request

If you already have an account please email cru@wakehealth.edu and include the following information:

Contact Name:                                              

Phone #: 

Pick-Up Date:

Time of Pick-Up:

Number of kg:

Please note if you need more than 10lbs of dry ice delivered your request will need to go through purchasing to Airgas.  We do not deliver.  Our CRU dry ice service is a courtesy for clinical trials that need small quantities to ship samples.  

CRU nurses and clinical research technicians provide patient care support for pediatric and adult research projects. 
Available services include:

• Anthropometric Measurements
• Basic Phlebotomy
• Bronchoscopy- Assist and Set-Up
• Cardiac Monitoring
• Clotting Time Procedures
• Conscious Sedation
• Continuous Blood Pressure Monitoring
• 12-Lead Electrocardiogram (ECG)
• Eye (chart) and Hearing Exams
• Frequently Sampled Intravenous Glucose Tolerance Test (FSIGT)
• Intramuscular and Subcutaneous Injections
• IV Infusions
• LP- Assist and Set-Up
• Medication Administration
• Melanin Scanning 
• Mental and Cognitive Testing
• Metered Walk Testing
• Muscle Biopsy- Assist and Set-Up
• Oral Glucose Tolerance Testing (OGTT)
• Pelvic Exams- Assist and Set-Up
• Pharmacokinetics (PK) Studies
• Pulse Oximetry
• Sample Collection (Blood, Sputum, Urine) (Including Saline Lock)
• Therapeutic Phlebotomy
• Vital Signs (Blood Pressure, Height, Weight, etc.)