PET Research Facility

Explore the many resources of the PET Research Facility

Index

CyclotronmicroPET/CT | Hot Cells | Quality Control | Other Services | Tracers

GE PETtrace 10 Cyclotron

PETtrace 10 Cyclotron

 

The GE PETtrace Radiotracer Production System is a compact, automated cyclotron and radiochemistry system designed for the fast, easy, and efficient production of PET radiotracers.  The PETtrace System is centered on a compact negative ion cyclotron of proven design.  The PETtrace Cyclotron features a vertical mid-plane and can accelerate protons to 16.5 MeV and deuterons to 8.4 MeV of energy.  The system can be configured with various targets/process systems for production of common PET radioisotopes.  The high performance, flexible design is ideal for applications in a research setting.

The PET isotopes, which can be produced by the PETtrace System, including oxygen-15, nitrogen-13, carbon-11, and fluorine-18, are automatically transferred to the radiochemistry processing systems for efficient conversion into finished radiotracers or precursors for use in preparing other labeled molecules.

 

Siemens Vision.X PET/CT Scanner

The Biograph Vision.X is a whole-body PET/CT tomograph designed for the purposes of oncological, neurological, and cardiac imaging and aid in diagnosis. With a single noninvasive procedure, the Biograph produces remarkable CT and PET/CT images that reveal highly detailed anatomy and biological processes at the molecular level.

The Biograph provides:
- high performance spiral computed tomography (CT) imaging and applications including Edge 128 slice capability.
- high-resolution, high-count rate, positron emission tomography (PET) imaging of metabolic and physiologic processes.
- high quality anatomic and metabolic image registration for optimal lesion detection and identification within the body.
- high quality attenuation correction and scatter correction for PET imaging.
In addition, the Biograph Vision.X uses a high-performance PET detector design to achieve our fastest time-of-flight performance to date. To best use the additional performance, the Biograph Vision.X includes UltraHD-PET standard.

-UltraHD-PET reconstruction, combining time-of-flight reconstruction with HD-PET resolution recovery.

-Wide, 78-cm bore and short, 136-cm tunnel for patient comfort and easy access

Trifoil InSyTe microPET/CT Scanner

This new, high performance PET benchtop system with in-line X-ray CT provides the ability to visualize and quantify biological processes over a wide range of PET tracer activities with a reconstructed isotropic image resolution of <1.0µl (<1mm). The InSyTe Lab PET system is the first preclinical PET with continuous bed motion PET detection, maintains uniform signal-to-noise sensitivity across the entire scan range.

 Hot Cells

Transis-All In One

Fx2M

CyclotronGE PET Trace 800 Series

FxMel

GE TRACERlab FxC

 Quality Control

ProStar 210UV-Varian HPLC 

ProStar 210 UV-Varian HPLC

 Waters Alliance HPLC

Waters Alliance HPLC

 Agilent 7890BGas Chromatography

Agilent 7890B Gas Chromatography

 Radio TLC Scanner

Radio TLC Scanner

 Other Services

Daily Sterility testing

 BET testing of radiopharmaceuticals

BET testing of radiopharmaceuticals

Tracers

Tracer
Application
[11C]PiB Imaging brain amyloidosis for AD  
[18F]AV1451 Imaging Tau protein aggregates for AD
[11C]Nicotine (inhalation) Nicotine uptake in pulmonary pathways
[11C]Nicotine (injection) Nicotine uptake in brain
[11C]AcOAc Ketone uptake in brain activity
[11C]PBR28 Inflammation imaging
[11C]MPC-6827 Microtubule imaging
[11C]Raclopride Dopamine D2/D3 receptor binding
[11C]Fallypride Dopamine D2/D3 receptor binding
[11C]NOP1
 Nociceptin Opioid receptor imaging
[11C]Acetate Metabolic uptake imaging
[18F]MeFDG Sodium-glucose linked transporter-2 (SGLT2) imaging
[18F]UCBH Synaptic vesicle 2A (SV2A) imaging
[11C]MK-6884
Muscarinic cholinergic receptor 4 (M4) imaging
[11C]EKAP Kappa opioid receptor (KOR) imaging