The major goal of the Central Biorepository Shared Resource (CBSR) is to establish a centralized repository to inventory, archive and distribute existing tissues and associated analytics, as well as, to promote and guide collection of future samples from across the research and clinical community.
Services
The CBSR is an enterprise-wide resource, serving all members of Wake Forest Baptist. The CBSR helps researchers access, collect, manage, and protect biospecimens using automated processes.
Available samples from an array of participants enrolled in a wide variety of research studies.
Investigators can use the self-serve tool LabKey to identify biospecimens of interest based on demographic, clinical, sample, and other parameters relevant to their research study. Researchers may also coordinate directly with the primary investigator to select samples. The Central Biorepository also serves as the custodian for biospecimens obtained through clinical biobank networks that have their own access procedures.
Providing the ability to bank, archive, and inventory in ultralow (-80°C) climate-controlled conditions. Two ways to store:
Managed Storage: Access is limited to CBSR personnel only. Freezers are monitored 24/7 and are connected to CO2 back up systems in the event of an operational failure. Detailed sample information is required in Excel format.
- Project Setup - $380
One-time fee per project, includes IT personnel consult for set up in LabKey, box and labels costs of 1st box, and personnel time to verify and log samples into LabKey
- Additional Box Setup - both include box and label costs along with personnel time to verify and log samples into LabKey
- Option 1 - $120 (CBSR receives individual samples at various timepoints)
- Option 2 - $50 (CBSR receives a box of 81 samples at once)
- Liquid Nitrogen Storage - $12 per month
Monthly charge for a 2-inch storage box
- -80°C Storage - $2 per month
Monthly charge for a 2-inch storage box
- Distribution of Samples - $12.50 per 15 minutes
- Long-term -80°C Storage - $3,300 per year
Yearly charge per freezer located in long-term storage area. A detailed sample inventory is required in Excel format
Services
- DNA Isolation from Whole Blood - $20 per sample
- DNA Isolation from PAXgene Blood DNA Tubes - $33 per sample
- DNA/RNA Isolation from Cells & Tissues - $25 per sample
- DNA/RNA Purity Analysis using Nanodrop - $2 per sample
- DNA/RNA Quantification using Qubit - $6 per sample
- DNA/RNA Analysis using TapeStation - $14 per sample
- PBMC processing of 8mL CPT Tube - $123 per sample
- Includes aliquots: 6 plasma, 2 PBMCs - Blood Processing from freshly collect Whole Blood
- Serum - $22 per sample
- Plasma - $22 per sample
- Buffy Coat – S29 per sample
- Plasma, WBC, and RBC form 10mL EDTA tube - $43 per sample
Services
- Biospecimen Transport - $25
- Shipping*
- Controlled Room Temperature (Small Box) - $84
- Dry Ice (Medium Box) - $66
*Shipping does NOT include the courier’s transportation fees which are billed at cost
Grant Support
CBSR also offers guidance for PIs that might propose to use samples, including providing SOPs and text for grant sections
