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Clinical Research Services from the CTSI Clinical Research Unit

The Clinical Research Unit (CRU) provides bionutrition, laboratory, and patient care services for approved studies. The CRU is comprised of two units within the institution on the main floor of the Progressive Care Building and the first floor of the Sticht Center for Aging.  CRU staff work closely with investigators and their study teams to provide high quality services for all types of studies including industry, federal, and investigator initiated sponsored research. 

Cost

Industry-Initiated
Investigator-Initiated: Early Career & Pilot Studies
Investigator-Initiated: Experienced Investigators with Extramural Funding

Ancillary Support

Investigators may apply for funding support to off-set study costs such as laboratory or imaging components of CRU-approved pilot studies. A formal request and approval process are required components for funding consideration.

Contact: Shepeara Hall: skhall@wakehealth.edu | 336-716-2302


Main Clinical Research Unit

  • 9 Exam Rooms
  • 1 Procedure Room
  • Metabolic Kitchen
  • Dining Room
  • CLIA-Certified Processing Core

Standard Operating Hours: 6:30 am - 4:30 pm.

Geriatric Clinical Research Unit

  • 5 Exam Rooms
  • Dining Room
  • Processing Laboratory

CRU Bionutrition is comprised of three main areas of support: food service, nutrition assessments, and nutritional education. Services Include:

  • Aliquot Preparation for Meal Assays
  • Anthropometric Body Measurements
  • Bioelectrical Impedance (BIA) Measurement
  • Collection and Analysis of Dietary Intake Data from Dietary Recalls or Records
  • Computer-Assisted Food Weigh-Back System
  • Computer-Assisted Menu Planning for Research Diets
  • Controlled Nutrient Diet Planning, Analysis, and Preparation
  • Development of Protocol-Specific Educational Materials
  • Dietary Compliance Monitoring and Assessment
  • Doubly-Labeled Water Testing
  • Vitamin, Mineral, and Herbal Supplement Intake Assessment
  • Food Frequency Questionnaire Administration and Analysis
  • Health Snacks for Fasting Visits
  • Indirect Calorimetry (RMR) Testing
  • Metabolic Kitchen Services
  • Nutrition Screening and Evaluation for Feeding Study Eligibility
  • Nutritional Status and Dietary History Assessments
  • On-Site and Pack-Out Research Meal Feeding
  • Recipe Development
  • Registered Dietician Services for Nutrition Counseling
  • Self-Monitoring Tools Development, Implementation, and Analysis

The CRU laboratory staff provide consultation on speciman collection and testing procedures as well as processing of blood, saliva, sputum, breast milk, urine, and fecal specimens in the Main and Geriatric Units. The laboratory is equipped with -70 freezers, refrigerators, refrigerated centrifuges, micro-centrifuges, micropipettes, and fume hoods. Available Services include:

  • Buffy Coat Purification
  • Collaboration with LabCorp and Institutional Core Laboratories
  • IV Glucose Tolerance Testing
  • Non-Waived Testing (YSI 2300 STAT Plus Glucose Analyzer)
  • Oral Glucose Tolerance Testing
  • Pharmacokinetic (PK) and Pharmacodynamic (PD) Specimen Processing
  • Preparation and Routing of Specimens for Immediate Analysis
  • Preservation of Specimens for Transport, Ambient, Refrigerated, and Frozen on Dry Ice
  • Processing of Blood, CSF, Specific Cells, Sputum, Saliva, Breast Milk, Urine, Feces, and Tissue
  • Real Time Results Reporting
  • Short-Term Repository Storage
  • Timed Urine Collection
  • Validation of Point of Care Testing Instruments, Including Development of QC and QA Programs

The Clinical Research Unit (CRU) is offering dry ice service, at cost, for research study needs.

Orders can be placed on an as needed basis or established as a standing weekly, monthly, bi-monthly, etc. order.

Cost

The cost, per kilogram, is $2.22 for investigator-initiated studies and $3.22 for industry-initiated studies.

Access

Please complete and email the information below to cru@wakehealth.edu.

  • Contact Name
  • Phone Number
  • Email Address
  • Frequency
  • Quantity
  • Pick-up Date(s)
  • Chartfield
  • Note

CRU nurses and clinical research technicians provide patient care support for pediatric and adult research projects. Available services include:

  • Ankle Brachial Index (ABI)
  • Autonomic Function Assessments
  • Basic Phlebotomy
  • Bronchoscopy- Assist and Set-Up
  • Cardiac Monitoring
  • Clotting Time Procedures
  • Complete Study-Specific Forms
  • Conscious Sedation
  • Eye (chart) and Hearing Exams
  • Frequently Sampled Intravenous Glucose Tolerance Test (FSIGT)
  • Intramuscular and Subcutaneous Injections
  • IV Medication Administration
  • LP- Assist and Set-Up
  • Mental and Cognitive Testing
  • Muscle Biopsy- Assist and Set-Up
  • Oral Glucose Tolerance Testing (OGTT)
  • Pharmacokinetics (PK) Studies
  • Sample Collection (Blood, Sputum, Urine) (Including Saline Lock)
  • Vital Signs (EKG, Blood Pressure, Height, Weight, etc.)

Working with the CRU

Learn more about what you need to know to access the Clinical Research Unit and how to schedule patient visits.

Access CRU Services


Access CTSI programs and request services or support through the CTSI Service Request Form.